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CMS Exclusionary Conditions for Organ Procurement

Exclusionary conditions are described in CMS Conditions of Coverage for Organ Procurement Organizations; Final Rule (71 Federal Register 30928).

Active Infections

  • Bacterial
  • Tuberculosis
  • Gangrenous bowel or perforated bowel and/or intra-abdominal sepsis

Fungal

  • Active infection with Cryptococcus, Aspergillus, Histoplasma, Coccidioides.
  • Active candidemia or invasive yeast infection.

Parasites
Active infection with Trypanosoma cruzi (Chagas'), Leishmania, Strongyloides, or Malaria (Plasmodium sp.).

Viral

  • HIV infection by serologic or molecular detection.
  • Rabies.
  • Reactive Hepatitis B Surface Antigen.
  • Retroviral infections including HTLV I/II.
  • Viral Encephalitis or Meningitis.
  • Active Herpes simplex, varicella zoster, or cytomegalovirus viremia or pneumonia.
  • Acute Epstein Barr Virus (mononucleosis).
  • West Nile Virus infection.
  • Severe acute respiratory syndrome (SARS).

Prion
Creutzfeldt-Jacob Disease.

General Exclusions

  • Aplastic Anemia.
  • Agranulocytosis.
  • Extreme Immaturity (<500 grams or gestational age of <32 weeks).
  • Current malignant neoplasms except non-melanoma skin cancers such as basal cell and squamous cell cancer and primary CNS tumors without evident metastatic disease.
  • Previous malignant neoplasms with current evident metastatic disease.
  • A history of melanoma
  • Hematologic malignancies: Leukemia, Hodgkin's Disease, Lymphoma, Multiple Myeloma.

Appendix A: Exclusionary conditions for eligibility for death

Exclusionary conditions are described in CMS Conditions of Coverage for Organ Procurement
Organizations; Final Rule (71 Federal Register 30928).

Active Infections

Bacterial

  • Tuberculosis
  • Gangrenous bowel or perforated bowel and/or intra-abdominal sepsis

Fungal

  • Active infection with Cryptococcus, Aspergillus, Histoplasma, Coccidioides.
  • Active candidemia or invasive yeast infection.

Parasites

  • Active infection with Trypanosoma cruzi (Chagas'), Leishmania, Strongyloides, or Malaria (Plasmodium sp.).

Viral

  • HIV infection by serologic or molecular detection.
  • Rabies.
  • Reactive Hepatitis B Surface Antigen.
  • Retroviral infections including HTLV I/II.
  • Viral Encephalitis or Meningitis.
  • Active Herpes simplex, varicella zoster, or cytomegalovirus viremia or pneumonia.
  • Acute Epstein Barr Virus (mononucleosis).
  • West Nile Virus infection.
  • Severe acute respiratory syndrome (SARS).

Prion

  • Creutzfeldt-Jacob Disease.

General Exclusions

  • Aplastic Anemia.
  • Agranulocytosis.
  • Extreme Immaturity (<500 grams or gestational age of <32 weeks).
  • Current malignant neoplasms except non-melanoma skin cancers such as basal cell and squamous cell cancer and primary CNS tumors without evident metastatic disease.
  • Previous malignant neoplasms with current evident metastatic disease.
  • A history of melanoma
  • Hematologic malignancies: Leukemia, Hodgkin's Disease, Lymphoma, Multiple Myeloma.